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BENECOL® Smart Chews and Spreads are the only products in the U.S. that contain Plant Stanol Esters, a dietary ingredient that lowers cholesterol and may reduce the risk of heart disease when used as part of a diet low in saturated fat and cholesterol. Plant stanol esters reduce the absorption of cholesterol in the digestive tract, resulting in lower total and LDL or "bad" cholesterol levels. For further information and to join Club BENECOL® to receive special offers and savings go to www.BenecolUSA.com.

Q: How quickly do plant stanol esters affect cholesterol levels?
Q: How much plant stanol esters should I consume per day for cholesterol lowering?
Q: Have any clinical studies been done to support the efficacy of BENECOL® Smart Chews?
Q: How many calories does each BENECOL® Smart Chews contain?
Q: What is the safety profile of BENECOL® Smart Chews?
Q: What is the maximum number of BENECOL® Smart Chews I can consume per day?
Q: Are there any drug-nutrient interactions with BENECOL® Products?
Q: How should patients with diabetes incorporate BENECOL® Smart Chews into their diets?

Q: How quickly do plant stanol esters affect cholesterol levels?
A. Clinical studies have demonstrated that plant stanol esters, the ingredient in BENECOL® Products, start to work in as little as two weeks.

Q: How much plant stanol esters should I consume per day for cholesterol lowering?
A. To lower your cholesterol you should consumer at least two BENECOL® Smart Chews (1.7 grams of Plant Stanol Esters) per day with your meals and snacks. For best results, consuming 4 BENECOL® Smart Chews daily will provide the 3.4 grams of plant stanol esters (2 grams of plant stanols) per day recommended by the National Cholesterol Education Program (NCEP).

Q: Have any clinical studies been done to support the efficacy of BENECOL® Smart Chews?
A. Over 25 published clinical studies support the safety and efficacy of plant stanol esters, the cholesterol lowering ingredient contained in BENECOL® Smart Chews. Based on the totality of this scientific evidence on the cholesterol- lowering efficacy of plant stanol esters, the Food and Drug Administration (FDA) allows its use in various foods and supplement products including BENECOL® Smart Chews.

Q: How many calories does each BENECOL® Smart Chews contain?
A. Each serving (one chew) contains 20 calories.

Q: What is the safety profile of BENECOL® Smart Chews?
A. Plant stanol esters, the unique ingredient contained in BENECOL® Smart Chews, has an excellent safety profile. In fact, plant stanol esters have been consumed by millions of individuals in Finland since 1995 and in other European countries and the United States since 1999.

Q: What is the maximum number of BENECOL® Smart Chews I can consume per day?
A. Up to 6 BENECOL® Smart Chews may be consumed per day. There is no evidence that exceeding an intake of 5.1 grams of plant stanol esters (6 BENECOL® Smart Chews) per day will provide any additional cholesterol lowering benefit.

Q: Are there any drug-nutrient interactions with BENECOL® Products?
A. No, there is no clinical evidence to indicate that BENECOL® Products will interfere with any medications. In clinical studies using plant stanol esters, the ingredient in BENECOL® Smart Chews, investigators identified a number of subjects using medication, but no reports of drug interactions were reported. Additionally, no drug interactions have been reported in the medical literature. In fact, when used in conjunction with statin medication therapy, BENECOL® Smart Chews have an additional cholesterol lowering effect.

Q: How should patients with diabetes incorporate BENECOL® Smart Chews into their diets?
A. BENECOL® Smart Chews contain only 4 grams of carbohydrate per chew, which can easily be incorporated into an appropriate meal plan for people with diabetes. It is recommended that BENECOL® Smart Chews be consumed with meals or snacks for optimal cholesterol lowering. A free food in a meal plan for people with diabetes is defined as containing less than 20 calories, or less than or equal to 5 grams of carbohydrate per serving. Therefore one BENECOL® Smart Chew, which contains 4 grams of carbohydrate per serving, qualifies as a "free food".


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