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High Blood Pressure ResearchThe following research focuses on new approaches to prevent and treat high blood pressure (hypertension) and its complications: Complications- Researchers are investigating new ways to prevent high blood pressure complications, and repair organs and tissues damaged by the condition.
- The Computerized Automatic Pressure Sensor and Inflator Device (CAPSID) is a computer-operated device that gradually inflates a balloon and stent inside a narrowed coronary artery. Research indicates that the device significantly reduces the long-term risk of re-narrowing of the coronary arteries and resulting complications (such as heart attack).
Diet- Studies have shown that cocoa-rich products (such as dark chocolate) can lower blood pressure. It is believed that the benefits are due to compounds known as polyphenols (or flavonoids). Although tea contains polyphenols, tea studies have not shown similar results.
- Soy products (such as soy nuts and soy milk) have been shown to help lower blood pressure.
Essential hypertension- Several studies are investigating genetic mutations that predispose people to developing essential hypertension.
- Prior studies have shown that arginine (an amino acid) helps dilate (widen) blood vessels. The effect of L-arginine metabolism on essential hypertension is currently being studied.
- Several studies are investigating the effectiveness of lifestyle changes on essential hypertension.
Inflammation- Researchers are investigating whether or not high blood pressure is an inflammatory disorder. Current studies are focusing on the involvement of the following proteins:
- Interleukin-6, which is a cytokine (immune system protein) that stimulates the immune response to tissue damage leading to inflammation.
- C-reactive protein, which is a byproduct of inflammation.
Medications- Several safer, more effective medications and medication delivery systems to prevent and treat high blood pressure are being researched.
Non-drug treatments- The Rheos Baroreflex Hypertension Therapy System is an implantable device designed to treat high blood pressure in people whose high blood pressure cannot be controlled with medications. The device stimulates the body's own regulatory systems to control high blood pressure.
Bystolic approvalIn December 2007, the Food and Drug Administration (FDA) approved nebivolol (Bystolic) a beta blocker not previously approved for the treatment of high blood pressure in the United States. Bystolic demonstrated additional blood pressure-lowering effects when given with up to two other antihypertensive medications in people with inadequate blood pressure control.New combination drugIn early 2008, the Food and Drug Administration (FDA) approved Tekturna HCT to treat high blood pressure. Tekturna HCT is a combination of the high blood pressure drug Tekturna (aliskiren) and the diuretic hydrochlorothiazide. Studies indicate that the combination drug provides greater blood pressure reductions than either of its components when used individually.
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