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Jarrow Formulas Natural SAM-e 200mg, Tablets 60 ea

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Dietary Supplement

S-Adenosyl Methionine
Highest Concentration of Active S,S Form


  • Longevity*
  • Joint Strength*
  • Liver Detoxification*
  • Mood and Brain Function*

Jarrow Formulas® pharmaceutical grade, stabilized SAM-e 200 provides a full 200mg SAM-e (net yield).  SAM-e is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.

Contains More of the Active S,S Form
Found in all living cells, SAM-e is a metabolite of methionine (an essential amino acid).  SAM-e is a chiral molecule and consists of two forms:  (S,S) SAM-e and (R,S) SAM-e.  The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive.  Jarrow Formulas SAM-e is made naturally by microbiological fermentation and then specially processed without solvents to preserve 68-80% (S,S) SAM-e, the highest active level available.

SAM-e has been clinically shown to have the following benefits:*

Joint Strength:  SAM-e supports the production of healthy connective tissue through transulfuration.  In this process, critical components of connective tissue, including glucosamine and the chondroitin sulfates, are sulfated by SAM-e metabolites*

Brain Metabolism:  SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine and related hormones, serotonin, epinephrine and phosphatidylcholine (a component of lecithin).*

Longevity:  Methylation of DNA appears to be important in the suppression of errors in DNA replication.  Demethylation of DNA is considered a contributor to the aging process.*  Proper methylation through substances such as SAM-e positively influences longevity.*

Liver:  SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase and glutathione-S-transferase), which are substances important for liver function.*

No wheat, no gluten, no soybeans, no dairy, no egg, no fish/shellfish, no peanuts/tree nuts.

Suitable for vegetarians/vegans

Made in Italy

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.


Individuals using prescribed medications such as antidepressants, including Selective Serotonin re-Uptake Inhibitors (SSRIs) and MAO Inhibitors should consult a physician before using.  Individuals with Parkinson's disease, bi-polar disorder or manic depression should not use SAM-e.  Keep out of each of children

©Jarrow Formulas

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