 Glucosamine is a carbohydrate, or complex sugar, that the body makes from sugar in foods. The body uses the substance to form cartilage, the protective tissue in joints. Glucosamine supplement, which is made from the shells of crabs and other shellfish, is said to decrease joint pain and improve joint movement among people with osteoarthritis. Select a glucosamine product from a reputable company such as >Nature Made, GNC, or Alfexa. This way, you can be more certain that the amount of the active ingredient listed on the product's label is actually in the product. Also consider using a chondroitin and glucosamine combination. Studies have shown that both glucosamine and chondroitin may be effective in reducing some people’s arthritis pain. Using a combination product may be more convenient, allowing you to take fewer pills each day. Several reliable combination products include Sundown, GNC and >Cosamin DS. Glucosamine doesn't work for everyone. If you don't notice an improvement in your symptoms after 8 weeks, it is unlikely that glucosamine will work for you. It also isn't intended to replace prescription medications or your doctor’s medical directions. If you do chose to take glucosamine, please let your doctor and pharmacist know. Sources:
Davis, W.M. "The Role of Glucosamine and Chondroitin Sulfate in the Management of Arthritis," Drug Topics Supplement (1998).
Kuhn, M.A. Herbs, Drugs & the Body, Medical Educational Services, Inc. 1999.
Deal, CL. “Nutraceuticals as Therapeutic Agents in Osteoarthritis. The Role of Glucosamine, Chondroitin Sulfate, and Collagen Hydrolysate,” Rheumatic Diseases Clinics of North America 25, (1999).
McAlindon, TE. “Glucosamine and Chondroitin for Treatment of Osteoarthritis: a Systematic Quality Assessment and Meta-Analysis,” Journal of the American Medical Association, 283(2000).
Drug Facts and Comparisons. Facts & Comparisons, 2007.
This answer prepared 12/13/2000.
This information updated 1/18/2007.
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