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Are there any prescription treatments for eczema?

Eczema—also known as dermatitis—is a red, itchy rash on the upper layers of the skin. Antiinflammatory steroid creams such as triamcinolone (Kenalog) or fluocinolone (>Synalar) can be prescribed for severe flare-ups not controlled by over-the-counter products.

A newer class of medicines called topical immunomodulators (TIMs) are prescribed for moderate to severe eczema that does not respond to other treatment. TIMs work by regulating the activity of the immune system. Medicines in this class include Pimecrolimus (>Elidel) and tacrolimus (>Protopic). These medicines are effective for flare-ups, but shouldn't be used on a continuous basis unless directed by your doctor. The FDA has some concerns regarding the long term use of these medicines on the immune system. These drugs are not approved for children under two years of age.

An infected eczema rash may need prescription antibiotic drugs. Antifungal drugs may also be appropriate in some cases. While these medications work to clear infections, they do little to help the eczema itself.

Over-the-counter moisturizers and steroid creams are usually the best ways to prevent eczema flare-ups and treat eczema.

Sources:
Mayo Clinic Family Health Book. William Morrow & Co., 1996.
The Merck Manual of Medical Information: Home Edition. Merck & Co., 1997.
Leung, D.Y., L. Diaz, V. DeLeo, N. Soter, "Allergic and Immunologic Skin Disorders" Journal of the American Medical Association. 278 (1997).
Micromedex® Healthcare Series. Thomson Micromedex, 2007.
Handbook of Nonprescription Drugs. American Pharmaceutical Association, 2000.
Diseases and Conditions, "Dermatitis/Eczema." http://www.mayoclinic.com. Mayo Clinic Health. Last accessed 1/9/2007.
Medline Plus. Medline, 2007.
Drug Facts and Comparisons. Facts & Comparisons, 2007.

This answer prepared 4/24/2002.
This information updated 1/9/2007.