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Are there any interactions with Coenzyme Q10?

Are there any interactions with Coenzyme Q10?


answer for 'Are there any interactions with Coenzyme Q10?'Coenzyme Q10 (CoQ10) is a vitamin-like chemical produced in the body from the amino acid tyrosine. CoQ10 and tyrosine are also present in a wide variety of foods, such as peanuts, soy oil, sardines, and organ meats. CoQ10 is important for the body to function normally. Some people claim it can help people with heart failure, unhealthy gums, low energy, poor immune systems, and cancer.

CoQ10's physical structure is similar to vitamin K. Vitamin K can interfere with the action of blood-thinning drugs such as Coumadin (generic name warfarin). Therefore, CoQ10 may also interfere with Coumadin. Speak to your doctor before trying CoQ10 if you are taking Coumadin.

Cholesterol-lowering drugs such as Mevacor (lovastatin) and Lopid (gemfibrozil) and the diabetes medicines, glyburide (Micronase), acetohexamide (Dymelor), and tolazamide (Tolinase), can lower the amount of CoQ10 in the body. You may want to raise your dose of CoQ-10 while you are taking cholesterol-lowering drugs. If you are diabetic you should talk to your doctor before taking this drug because it can lower the body's blood sugar levels.

Sources:
Landbo, C. "Interactions between warfarin and coenzyme Q10." Ugeskr Langer 4916 (1988).
Pepping, J. "Alternative Therapies: Coenzyme Q10." American Journal of Health-System Pharmacists 56 (1999).
The Natural Medicines Comprehensive Database. Pharmacists Letter Inc., 2000.
Micromedex® Healthcare Series. Thomson Micromedex, 2007.
Drug Facts and Comparisons. Facts & Comparisons, 2007.

This answer prepared 5/17/2000.
This information updated 1/17/2007.

  • Coenzyme Q10
  • >lovastatin
  • >gemfibrozil
  • >glyburide
  • >tolazamide

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