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Are there any interactions with Sonata?

Sonata (generic name zaleplon) is a prescription medicine for people who have trouble sleeping, a condition known as insomnia.

Cimetidine (brand name Tagamet), a drug used to reduce stomach acid, raises the level of Sonata in the body. This can cause more side effects and drowsiness. People who are taking both cimetidine and Sonata may need a lower dose of Sonata.

Be extra cautious if you take Sonata along with other drugs that cause drowsiness. The combination may lead to increased drowsiness. For the same reason, avoid alcohol when taking Sonata.

Drugs such as phenobarbital, phenytoin (Dilantin), rifampin (Rifadin), and carbamazepine (Tegretol) may decrease the effectiveness of Sonata.

Sources:
Sonata Product Information. King Pharmaceuticals Inc., 2006.
Micromedex® Healthcare Series. Thomson Micromedex, 2006.
Doghramji,PP. “Treatment of Insomnia with Zaleplon, a Novel Sleep Medication.” Internal Journal of Clinical Practice 55 (2001).
Medline Plus. Medline, 2006.
Drug Facts and Comparisons. Facts & Comparisons, 2006

This answer prepared 8/10/2001.
This information updated 11/30/2006.

>Cimetidine
>phenobarbital
>phenytoin
>rifampin
>carbamazepine

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