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 | Do any drugs interact with baclofen?
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|  Baclofen (brand name Lioresal) is a medicine used to treat the muscle spasms, cramping, and tightness that affect many people with multiple sclerosis, spinal cord conditions, or tardive dyskinesia. It relaxes muscles by acting on the brain and spinal cord.Baclofen can interact with tricyclic antidepressants, such as imipramine (Tofranil), clomipramine (Anafranil), and amitriptyline (Elavil). This combination can result in memory loss and reduced muscle strength. If you are taking other medicines, be sure to tell your doctor and pharmacist about them before you start taking baclofen. Sources:
Drug Facts and Comparisons. Facts and Comparisons, 2000.
Drug Information Handbook. American Pharmaceutical Association, 1999.
Micromedex Healthcare Series. Micromedex, Inc., 2000.
USP-DI Advice for the Patient: Drug Information in Lay Language. Micromedex Inc., 1998.
This answer prepared 8/8/00.
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