ask your pharmacist

Are there any interactions with Aricept?

Certain drugs such as ketoconazole (Nizoral), bethanechol (Urecholine), erythromycin (Ery-Tab), and quinidine increase the risk of side effects from Aricept. Carbamazepine (Tegretol), dexamethasone, phenytoin (Dilantin), phenobarbital, and rifampin (Rifadin) may decrease the effectiveness of Aricept. Other medications, including oxybutynin (Ditropan) and tolterodine (Detrol), may not work as well when combined with Aricept.

If you take Aricept, check with your doctor before using nonsteroidal anti-inflammatory pain medicines such as ibuprofen (Advil or Motrin), naproxen (Naprosyn or Aleve), or ketoprofen (Orudis). These drugs can increase your risk of stomach ulcers or stomach bleeding when you take them with Aricept.

Sources:
Aricept product information, Eisai Inc./Pfizer Inc.,2006.
Birks J S, Melzer D. “Donepezil for Mild and Moderate Alzheimer's Disease (Cochrane Review).” The Cochrane Library, Issue 3, 2000. Oxford: Update Software.
Drug Facts and Comparisons. Facts & Comparisons, 2006.
Birks J S, Melzer D. “Donepezil for Mild and Moderate Alzheimer's Disease (Cochrane Review).” The Cochrane Library, Issue 3, 2000. Oxford: Update Software.
Micromedex® Healthcare Series. Thomson Micromedex, 2006.

This answer prepared: 8/24/2000.
This information updated 1/25/2007.

• >ketoconazole
• >bethanechol
• >erythromycin
• >Carbamazepine
• >dexamethasone
• >phenytoin
• >phenobarbital
• >rifampin
• >Rifadin
• >oxybutynin
• >Detrol
• >ibuprofen
• >naproxen
• >ketoprofen