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What is Gleevec?

Gleevec (generic name imatinib) is an anti-cancer drug approved by the FDA to treat patients with chronic myeloid leukemia (CML). CML is an abnormal growth of white blood cells. CML is usually associated with a unique chromosome abnormality called the Philadelphia chromosome.

Gleevec is the first anti-cancer drug that is designed to specifically target cancer cells. Older cancer medications kill both cancer and healthy cells, leading to a higher risk of side effects. Gleevec works by blocking a protein that stimulates the growth of abnormal white blood cells.

Gleevec should be taken with food and a large glass of water.

The maker of Gleevec, Novartis, has set up a patient product information line for patients who need further assistance and information about Gleevec. To reach the product information service contact Novartis at 1-877-GLEEVEC.

Sources:
“Oncology.” Pharmacist’s Letter. 17 (6). Pharmacists Letter Inc., 2001.
Drug Facts and Comparisons., Facts and & Comparisons, 2006.
Gleevec Product Information. Novartis, Pharmaceuticals Corporation 2006.
Micromedex® Healthcare Series. Thomson Micromedex, 2006.

This answer prepared 7/2/2001.
Information last reviewed on 1/23/2007.

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