Learn more about usage, cautions, and possible side effects .
Chemical Name: METOPROLOL (me-TOE-proe-lole) and HYDROCHLOROTHIAZIDE (hye-droe-klor-oh-THYE-a-zide)
This medicine is a beta-blocker and thiazide diuretic combination used to treat high blood pressure.
WARNING: If you have angina or have had heart problems, do not suddenly stop using this medicine without first consulting your doctor. If your doctor decides you should no longer use this medicine, you must stop this medicine gradually according to your doctor's instructions. Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. DO NOT TAKE THIS MEDICINE if you are also taking dofetilide or mibefradil. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking amiodarone, barbiturates, cimetidine, clonidine, digitoxin, digoxin, disopyramide, flecainide, ketanserin, lithium, diazoxide, indomethacin, prazosin, quinidine, verapamil, birth control pills, or medicine for thyroid conditions. Inform your doctor of any other medical conditions, allergies, pregnancy, or breast-feeding. USE OF THIS MEDICINE IS NOT RECOMMENDED if you have a history of heart block. Contact your doctor or pharmacist if you have any questions or concerns about taking this medicine.
Follow the directions for using this medicine provided by your doctor. THIS MEDICINE MAY CAUSE an increase in urine or in frequency of urination. To prevent this from affecting sleep: if you are taking 1 dose daily, take it in the morning after breakfast. If you are taking more than 1 dose, take the last one no later than 6 pm. STORE THIS MEDICINE at room temperature in a tightly-closed container, away from heat and light. IF YOU MISS A DOSE OF THIS MEDICINE, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
IF YOU HAVE HAD A SEVERE ALLERGIC REACTION to this medicine or any other sulfonamide medicine (such as Septra DS, Bactrim DS, Gantrisin, glyburide, or probenecid), contact your doctor or pharmacist before taking this medicine. A severe reaction includes a severe rash, hives, breathing difficulties, or dizziness. If you have a question about whether you are allergic to this medicine or if a certain medicine is a sulfonamide, contact your doctor or pharmacist. DO NOT STOP TAKING THIS MEDICINE before checking with your doctor. BEFORE YOU HAVE ANY MEDICAL OR DENTAL TREATMENTS, EMERGENCY CARE, OR SURGERY, tell the doctor or dentist that you are using this medicine. DO NOT DRIVE, OPERATE MACHINERY, OR DO ANYTHING ELSE THAT COULD BE DANGEROUS until you know how you react to this medicine. Using this medicine alone, with other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks. THIS MEDICINE MAY CAUSE increased sensitivity to the sun. Avoid exposure to the sun or sunlamps until you know how you react to this medicine. Use a sunscreen or protective clothing if you must be outside for a prolonged period. YOUR DOCTOR MAY HAVE ALSO PRESCRIBED a potassium supplement for you. If so, follow the dosing carefully. Do not start taking additional potassium on your own or change your diet to include more potassium without first checking with your doctor. BEFORE TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. This includes decongestants such as phenylpropanolamine. FOR WOMEN: IF YOU PLAN ON BECOMING PREGNANT, discuss with your doctor the benefits and risks of using this medicine during pregnancy. THIS MEDICINE IS EXCRETED IN BREAST MILK. DO NOT BREAST-FEED while taking this medicine. FOR PATIENTS WITH DIABETES MELLITUS: this medicine may mask signs of low blood sugar such as a rapid heart rate. Check blood glucose levels regularly.
SIDE EFFECTS, that may go away during treatment, include dizziness or lightheadedness, headache, mild drowsiness, or unusual tiredness. If they continue or are bothersome, check with your doctor. CHECK WITH YOUR DOCTOR AS SOON AS POSSIBLE if you experience difficulty breathing, muscle pain or cramps, weakness, or rapid or irregular heartbeat. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your healthcare provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Drug interactions can result in unwanted side effects or prevent a medicine from doing its job. Use our drug interaction checker to find out if your medicines interact with each other. Check drug interactions
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include slow heart rate, dizziness, weakness, fainting, coughing, and trouble breathing.
DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children and pets. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out.
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