Learn more about usage, cautions, and possible side effects .
Chemical Name: NATEGLINIDE (neh-TEGG-lin-ide)
This medicine is a blood glucose-lowering agent used alone or in combination with metformin to treat type 2 (non-insulin dependent) diabetes mellitus. It is used along with diet and exercise. This medicine may also be used in combination with medicines called thiazolidinediones such as rosiglitazone if control of blood sugar has not been achieved with the thiazolidinedione alone. This medicine may be used for other conditions as determined by your doctor.
Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking monoamine oxidase inhibitors (MAOIs) (such as phenelzine), nonsteroidal anti-inflammatory agents (NSAIDs) (such as ibuprofen) , salicylates (such as aspirin), beta-blockers (such as metoprolol), thiazide diuretics (such as hydrochlorothiazide), gemfibrozil, imidazoles (such as ketoconazole), rifampin, corticosteroids (such as prednisone), sympathomimetics (such as pseudoephedrine), or thyroid hormones (such as levothyroxine). Inform your doctor of any other medical conditions including fever, infection, moderate to severe injury, allergies, pregnancy, or breast-feeding. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you have adrenal, pituitary, kidney or liver problems. USE OF THIS MEDICINE IS NOT RECOMMENDED if you have history of acidosis or type 1 (insulin-dependent) diabetes. Contact your doctor or pharmacist if you have any questions or concerns about taking this medicine.
Follow the directions for using this medicine provided by your doctor. This medicine must be taken 1 to 30 minutes before meals generally three times daily. If you skip a meal, you should skip your dose of this medicine to reduce your risk of developing hypoglycemia (low blood sugar). STORE THIS MEDICINE at room temperature at 77 degrees F (25 degrees C) in a tightly-closed container, away from heat and light. Brief storage between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Since this drug is generally given only before meals, consult your doctor or pharmacist regarding advice on a missed dose.
DO NOT TAKE THIS MEDICINE if you have had an allergic reaction to it or if you are allergic to any ingredient in this product. DO NOT STOP USING THIS MEDICINE without first checking with your doctor. DO NOT EXCEED THE RECOMMENDED DOSE without checking with your doctor. FOLLOW THE DIETARY PLAN provided by your doctor. THIS MEDICINE MAY CAUSE HYPOGLYCEMIA (low blood sugar). Signs of hypoglycemia include increased heartbeat, headache, chills, sweating, tremor, increased hunger, changes in vision, nervousness, weakness, dizziness, drowsiness, or fainting. It is a good habit to carry glucose tablets or gel to treat low blood sugar. If you do not a reliable source of glucose available, eat a quick source of sugar such as table sugar, honey, or candy, or drink a glass of orange juice or non-diet soda to quickly raise your blood sugar level. TELL YOUR DOCTOR IMMEDIATELY about the reaction. To prevent hypoglycemia, eat meals on a regular schedule and do not skip meals. DO NOT DRIVE, OPERATE MACHINERY, OR DO ANYTHING ELSE THAT COULD BE DANGEROUS until you know how you react to this medicine. Using this medicine alone, with other medicines, or with alcohol, may lessen your ability to drive or to perform other potentially dangerous tasks. BEFORE YOU HAVE ANY MEDICAL OR DENTAL TREATEMENTS, EMERGENCY CARE, OR SURGERY, tell the doctor or dentist that you are using this medicine. CONTACT YOUR DOCTOR if you have a fever, an infection, or a moderate to severe injury. Your blood sugar levels may be affected. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. THIS MEDICINE IS NOT RECOMMENDED for use during pregnancy. Insulin therapy may be necessary during pregnancy. Consult your doctor for more details. IT IS UNKNOWN IF THIS MEDICINE IS EXCRETED in breast milk. DO NOT BREAST-FEED while taking this medicine.
SIDE EFFECTS that may occur while taking this medicine include dizziness, increased heartbeat, flu-like symptoms (fever, chills, sore throat), headache, joint pain, sweating, tremor, increased hunger, changes in vision, nervousness,tiredness, or upper respiratory tract infection. If they are severe or continue to occur, check with your doctor. CONTACT YOUR DOCTOR IMMEDIATELY if you experience fever, stomach pain, or yellowing of the skin or eyes. AN ALLERGIC REACTION TO THIS MEDICINE is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash, itching, swelling, dizziness, or trouble breathing. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your healthcare provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Drug interactions can result in unwanted side effects or prevent a medicine from doing its job. Use our drug interaction checker to find out if your medicines interact with each other. Check drug interactions
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include headache, sweating, shakiness, increased hunger, changes in vision, nervousness, tiredness, seizures, and loss of consciousness.
Proper diet, regular exercise, and regular testing of blood sugar are important for best results when using this medicine. Follow your doctor's instructions carefully. Carry an identification card at all times that says you are diabetic. Monitor your blood sugar levels regularly according to your doctor's directions. If your blood sugar level is often higher than it should be and you are taking this medicine according to directions, check with your doctor. DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children and pets. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, be sure to obtain more necessary refills before your supply runs out.
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