Learn more about usage, cautions, and possible side effects .
Chemical Name: NITROGLYCERIN (NYE-troe-GLIS-er-in)
This medicine is a nitrate used for preventing chronic chest pain caused by heart disease. It also may be used for other conditions as determined by your doctor.
Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. DO NOT TAKE THIS MEDICINE IF you are taking a phosphodiesterase type 5 inhibitor (eg, sildenafil). ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking beta-blockers (eg, propranolol), calcium channel blockers (eg, diltiazem), diuretics (eg, furosemide, hydrochlorothiazide), medicines for high blood pressure, phenothiazines (eg, thioridazine), salicylates (eg, aspirin), or alteplase. DO NOT START OR STOP any medicine without doctor or pharmacist approval. Inform your doctor of any other medical conditions, including anemia, low blood pressure, dehydration, low blood volume, allergies, pregnancy, or breast-feeding. Tell your doctor if you have a history of other heart problems (eg, heart failure, enlarged heart, heart attack); overactive thyroid; stroke or other bleeding in the brain; or recent head injury. Tell your doctor if you drink alcoholic beverages. USE OF THIS MEDICINE IS NOT RECOMMENDED if you are allergic to the adhesive that makes the patch stick to your skin; you have increased pressure in or severe injury to the head; or if you have severe anemia. This medicine is not recommended for use in CHILDREN; safety and effectiveness in children have not been confirmed. Contact your doctor or pharmacist if you have any questions or concerns about using this medicine.
Follow the directions for taking this medicine provided by your doctor. AN EXTRA PATIENT LEAFLET is available with this medicine. Talk to your pharmacist if you have questions about this information. THIS MEDICINE IS FOR EXTERNAL USE ONLY. Apply the patch at the same time every day. WASH YOUR HANDS thoroughly before and after applying the patch. APPLY THE PATCH TO a non-hairy area of the chest, inner side of the upper arm, back, or shoulder. CLEAN AND COMPLETELY DRY THE SKIN BEFORE APPLYING the patch. If necessary, hair should be removed by clipping or lightly shaving. Remove the patch from the package. Apply with a firm pressure to the skin. TO AVOID SKIN IRRITATION, change the treatment site daily. DO NOT APPLY TO irritated or damaged skin. IF THE PATCH BECOMES LOOSE, remove it and apply a new patch at a different site. AFTER REMOVING THE USED PATCH, fold it in half with the sticky sides together. Discard the patch out of the reach of children and away from pets. THIS PATCH SHOULD ONLY BE WORN FOR UP TO 12 TO 14 HOURS A DAY, or as directed by your doctor, so that you will have a 10 to 12 hour "nitrate-free" period each day. Do not use more of this medicine than prescribed. It is important to have a "nitrate-free" period of time each day for this medicine to continue to work well and to decrease the risk of physical dependence. STORE THIS MEDICINE at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), away from heat, moisture, and light. Do not store in the bathroom. IF YOU MISS A DOSE of this medicine, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
DO NOT USE THIS MEDICINE IF you are allergic to any ingredient in this medicine. WHEN USED FOR AN EXTENDED PERIOD OF TIME, this medicine may not work as well. Increasing the dose is not effective in managing tolerance to this medicine. Talk with your doctor if this medicine stops working well. DO NOT EXCEED THE RECOMMENDED DOSE or take this medicine for longer than prescribed. Exceeding the recommended dose or taking this medicine for longer than prescribed may be habit-forming. DO NOT SUDDENLY STOP USING THIS MEDICINE without first checking with your doctor. If you suddenly stop using this medicine you may get withdrawal symptoms (eg, chest pain, heart attack, sudden death). Be sure to have a "nitrate-free" period each day to help prevent tolerance, dependence, and withdrawal. LAB TESTS, including heart function, blood pressure, and blood electrolyte levels, may be performed while you use this medicine. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments. THIS MEDICINE MAY CAUSE DIZZINESS, LIGHTHEADEDNESS, OR BLURRED VISION. These effects may be worse if you take it with alcohol or certain medicines. Use this medicine with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it. CHECK WITH YOUR DOCTOR BEFORE YOU DRINK ALCOHOL while you are taking this medicine. Drinking alcohol may increase the risk of low blood pressure with this medicine. THIS MEDICINE MAY CAUSE DIZZINESS, LIGHTHEADEDNESS, OR FAINTING. Sit down while taking this medicine to avoid falling caused by lightheadedness or dizziness. CONTACT YOUR DOCTOR RIGHT AWAY IF YOU DEVELOP slow heartbeat or new or worsening chest pain after you take this medicine. TELL YOUR DOCTOR OR DENTIST THAT YOU TAKE THIS MEDICINE before you receive any medical or dental care, emergency care, or surgery. THIS MEDICINE MAY GIVE YOU DAILY HEADACHES. This should become less noticeable with time. OTHER DOSAGE FORMS OF THIS MEDICINE (eg, sublingual, or under the tongue, tablets) may not work as well while you are taking this medicine. THIS MEDICINE TAKES ABOUT 1 TO 2 HOURS TO START WORKING and should not be used for a sudden chest pain attack. BEFORE YOU BEGIN TAKING ANY NEW MEDICINES, either prescription or over-the-counter, check with your doctor or pharmacist. Use this medicine with caution in the ELDERLY; they may be more sensitive to its effects. FOR WOMEN: IF YOU BECOME PREGNANT, contact your doctor. You will need to discuss the benefits and risks of using this medicine while you are pregnant. IT IS NOT KNOWN IF THIS MEDICINE IS FOUND in breast milk. IF YOU ARE OR WILL BE BREAST-FEEDING while you are using this medicine, check with your doctor. Discuss any possible risks to your baby.
SIDE EFFECTS that may occur while taking this medicine include dizziness, lightheadedness, or fainting when sitting up or standing; flushing of face and neck; headache; irritation at site of patch; nausea; or vomiting. If they continue or are bothersome, check with your doctor. CONTACT YOUR DOCTOR IMMEDIATELY if you experience blurred vision; dry mouth; fainting; flushing; heavy sweating; irregular heartbeat; new or worsening chest pain; pale skin; pounding in the chest; rapid heartbeat; severe dizziness or headache; severe or persistent nausea or vomiting; shortness of breath; slow heartbeat; swelling of the hands, ankles, or feet; or unusual weakness. AN ALLERGIC REACTION to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Drug interactions can result in unwanted side effects or prevent a medicine from doing its job. Use our drug interaction checker to find out if your medicines interact with each other. Check drug interactions
If overdose is suspected, remove the patch. Contact your local poison control center or emergency room immediately. Symptoms of overdose may include cold or blue skin; confusion; diarrhea; excessive sweating; fainting; fast, slow, or irregular heartbeat; persistent throbbing headache; seizures; trouble breathing; vision problems.
DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children and pets. IF YOU WILL BE USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, be sure to obtain necessary refills before your supply runs out.