Learn more about usage, cautions, and possible side effects .
Chemical Name: ATENOLOL (a-TEN-oh-lol) and CHLORTHALIDONE (klor-THAL-i-done)
This medicine is a beta blocker and diuretic combination used to treat high blood pressure.
Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. DO NOT TAKE THIS MEDICINE IF you are taking mibefradil. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking antiarrhythmics (eg, amiodarone, disopyramide, lidocaine, quinidine); bupivacaine; calcium channel blockers (eg, verapamil); digitalis (eg, digoxin); flecainide; ketanserin; mefloquine; clonidine; indomethacin; stimulants (eg, pseudophedrine); alpha-blockers (eg, doxazosin); diazoxide; lithium; or reserpine. DO NOT START OR STOP any medicine without doctor or pharmacist approval. Inform your doctor of any other medical conditions, including if you have an untreated adrenal gland tumor; diabetes; gout; liver problems; an overactive thyroid; systemic lupus erythematosus (SLE; lupus); a history of severe allergic reactions to allergens; asthma; chronic bronchitis; chronic obstructive pulmonary disease; emphysema; lung disease; congestive heart failure; slow heartbeat; heart rhythm problems; narrowing of blood vessels of the legs, arms, stomach, or kidneys; kidney problems; low blood potassium or low blood sodium; allergies; pregnancy; or breast-feeding. Tell your doctor if you are scheduled to have surgery or to receive anesthesia. USE OF THIS MEDICINE IS NOT RECOMMENDED if you have congestive heart failure that has not been treated; a very slow heartbeat; certain types of irregular heartbeat (eg, moderate to severe heart block); or if you are unable to urinate. Use of this medicine in children is not recommended. Discuss with your doctor the benefits and risks of giving this medicine to your child. Contact your doctor or pharmacist if you have any questions or concerns about using this medicine.
Follow the directions for taking this medicine provided by your doctor. TAKE THIS MEDICINE with or without food. This medicine may increase the amount of urine or cause you to urinate more often when you first start taking it. To keep this from disturbing your sleep, try to take your dose before 6 pm. STORE THIS MEDICINE at room temperature, between 68 and 77 degrees F (20 and 25 degrees C) away from heat, moisture, and light. Do not store in the bathroom. Taking this medicine at the same time each day will help you remember to take it. Continue to use this medicine even if you feel well. Do not miss any doses. IF YOU MISS A DOSE OF THIS MEDICINE, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. DO NOT take 2 doses at once.
DO NOT USE THIS MEDICINE IF you are allergic to any ingredient in this medicine or to any other sulfonamide, such as acetazolamide, celecoxib, hydrochlorothiazide, glyburide, probenecid, sulfamethoxazole, or zonisamide. THIS MEDICINE MAY CAUSE DROWSINESS, DIZZINESS, LIGHTHEADEDNESS, OR FAINTING. Alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects. These effects may be worse if you take it with alcohol or certain medicines. Use this medicine with caution. DO NOT DRIVE OR PERFORM OTHER POSSIBLY UNSAFE TASKS until you know how you react to it. THIS MEDICINE MAY CAUSE YOU TO BECOME SUNBURNED MORE EASILY. Avoid the sun, sunlamps, or tanning booths until you know how you react to this medicine. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.Be careful when you are out in the cold for long periods of time. Ask your doctor for more information. IF YOU HAVE A HISTORY OF ANY SEVERE ALLERGIC REACTION, talk with your doctor. You may be at risk for an even more severe allergic reaction if you come into contact with the substance that caused your allergy. TELL YOUR DOCTOR OR DENTIST THAT YOU TAKE THIS MEDICINE before you receive any medical or dental care, emergency care, or surgery. YOUR DOCTOR MAY HAVE ALSO PRESCRIBED A POTASSIUM SUPPLEMENT FOR YOU. DO NOT START taking additional potassium on your own or change your diet to include more potassium without first checking with your doctor. DO NOT SUDDENLY STOP TAKING THIS MEDICINE. Sharp chest pain, irregular heartbeat, and sometimes heart attack may occur if you suddenly stop this medicine. The risk may be greater if you have certain types of heart disease. Your doctor should slowly lower your dose over several weeks if you need to stop taking it. This should be done even if you only take this medicine for high blood pressure. Heart disease is common and you may not know you have it. LIMIT PHYSICAL ACTIVITY while you are lowering your dose. IF NEW OR WORSENED CHEST PAIN OR OTHER HEART PROBLEMS OCCUR, contact your doctor right away. You may need to start taking this medicine again. Lab tests, such as electrolyte and blood pressure monitoring, may be performed to monitor your condition or check for side effects. KEEP ALL DOCTOR AND LAB APPOINTMENTS while you are taking this medicine. BEFORE YOU BEGIN TAKING ANY NEW MEDICINES, either prescription or over-the-counter, check with your doctor or pharmacist. FOR WOMEN: THIS MEDICINE HAS BEEN SHOWN TO CAUSE HARM to the fetus. If you think you may be pregnant, contact your doctor to discuss the benefits and risks of using this medicine while you are pregnant. THIS MEDICINE IS FOUND in breast milk. IF YOU ARE OR WILL BE BREAST-FEEDING while you use this medicine, check with your doctor. Discuss any possible risks to your baby. DIABETES PATIENTS: This medicine may affect your blood sugar. It may also hide signs of low blood sugar, such as a rapid heartbeat. Be sure to watch for other signs of low blood sugar. Low blood sugar may make you anxious, sweaty, weak, dizzy, drowsy, or faint. It may also make your vision change; give you a headache, chills, or tremors; or increase your appetite. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
SIDE EFFECTS that may occur while taking this medicine include cold fingers or toes; diarrhea; dizziness; drowsiness; headache; lack of energy; lightheadedness; nausea; or tiredness. If they continue or are bothersome, check with your doctor. CONTACT YOUR DOCTOR IMMEDIATELY if you experience blue fingernails, toenails, or palms; decreased urination; fainting; fast, slow, or irregular heartbeat; increased thirst; mental or mood changes (eg, depression); muscle pain, cramps, or weakness; restlessness; severe joint pain (especially in the big toe); severe or persistent dizziness, drowsiness, or weakness; severe or persistent nausea, vomiting, or dry mouth; sluggishness; swelling of the hands or feet; trouble breathing; unusual bruising or bleeding; or yellowing of the skin and eyes. AN ALLERGIC REACTION to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your healthcare provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Drug interactions can result in unwanted side effects or prevent a medicine from doing its job. Use our drug interaction checker to find out if your medicines interact with each other. Check drug interactions
IF OVERDOSE IS SUSPECTED, contact your local poison control center or emergency room immediately. Symptoms of overdose may include confusion; fainting; severe dizziness or weakness; severe nausea; severe tiredness or sluggishness; shortness of breath or trouble breathing; slow or irregular heartbeat; or wheezing.
PATIENTS WHO TAKE MEDICINE FOR HIGH BLOOD PRESSURE often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel "normal". Tell your doctor if you develop any new symptoms. THIS MEDICINE MAY REDUCE THE AMOUNT OF BLOOD THAT FLOWS TO YOUR FEET AND HANDS. This may cause them to feel cold and make you more sensitive to the cold. Dress warmly in cold weather. DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children and pets. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out.
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