Learn more about usage, cautions, and possible side effects .
Chemical Name: TOPIRAMATE (toe-PIR-a-mate)
This medicine is an anticonvulsant used alone or with other medicines to control certain types of seizures. It may be also used to prevent migraine headaches or to treat other conditions as determined by your doctor.
Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. DO NOT TAKE THIS MEDICINE if you are also taking a carbonic anhydrase inhibitor (eg, acetazolamide). ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking hormonal birth control (eg, birth control pills), carbamazepine, hydantoins (eg, phenytoin), lithium, anticholinergics (eg, benztropine), tricyclic antidepressants (eg, amitriptyline), haloperidol, valproic acid, metformin, pioglitazone, hydrochlorothiazide, or risperidone. DO NOT START OR STOP ANY MEDICINE without doctor or pharmacist approval. Inform your doctor of any other medical conditions including a history of status epilepticus (continuous seizure activiy or a series of seizures without a full return to consciousness),glaucoma, liver or kidney problems, kidney stones, kidney dialysis, osteoporosis (weak bones), metabolic problems, lung or breathing problems, low bicarbonate levels in the blood, allergies, pregnancy, or breast-feeding. Tell your doctor if you have a history of mental or mood problems, or suicidal thoughts or actions. Tell your doctor if you have diarrhea, are on a ketogenic diet, drink alcohol, or you will be having surgery. Contact your doctor or pharmacist if you have any questions or concerns about taking this medicine.
Follow the directions for using this medicine provided by your doctor. This medicine has a MEDICATION GUIDE approved by the U.S. Food and Drug Administration. Read it carefully. Ask your doctor, nurse, or pharmacist any questions that your may have about this medicine. SWALLOW WHOLE. Do not break, crush, or chew before swallowing. This medicine may be taken on an empty stomach or with food. DRINKING EXTRA FLUIDS while you are taking this medicine is recommended. Check with your doctor or nurse for instructions. STORE THIS MEDICINE at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly-closed container, away from heat and light. Do not suddenly stop taking this medicine. Suddenly stopping this medicine may cause seizures to occur more often. If you need to stop this medicine, your doctor will gradually lower your dose. IF YOU MISS A DOSE OF THIS MEDICINE, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.
DO NOT TAKE THIS MEDICINE if you have had an allergic reaction to it or are allergic to any ingredient in this product. KEEP ALL DOCTOR AND LABORATORY APPOINTMENTS while you are using this medicine. Laboratory and/or medical tests may be done before you start taking this medicine and during therapy to monitor for side effects. BEFORE YOU HAVE ANY MEDICAL OR DENTAL TREATMENTS, EMERGENCY CARE, OR SURGERY, tell the doctor or dentist that you are taking this medicine. THIS MEDICINE WILL ADD TO THE EFFECTS OF ALCOHOL and other depressants. DO NOT DRIVE, OPERATE MACHINERY, OR DO ANYTHING ELSE THAT COULD BE DANGEROUS until you know how you react to this medicine. Using this medicine alone, with other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks. THIS MEDICINE MAY REDUCE SWEATING which could raise your body temperature, especially in children. The risk of this serious side effect is greater in hot weather and/or during vigorous exercise. Drink plenty of fluids and dress lightly while in hot climates, or when exercising. Check carefully for signs of decreased sweating. If this occurs, promptly seek cooler or air-conditioned shelter and/or stop exercising. SEEK IMMEDIATE MEDICAL ATTENTION if your body temperature is above normal, or if you have mental or mood changes, headache, or dizziness. THIS MEDICINE MAY CAUSE HIGH BLOOD ACID LEVELS (METABOLIC ACIDOSIS). Contact your doctor immediately if you experience fast breathing, unusual weakness or fatigue, sluggishness, fainting, persistent loss of appetite, or irregular heartbeat. PATIENTS WHO TAKE THIS MEDICINE MAY BE AT INCREASED RISK FOR SUICIDAL THOUGHTS OR ACTIONS. The risk may be greater in patients who have had suicidal thoughts or actions in the past. Watch patients who take this medicine closely. Contact the doctor at once if new, worsened, or sudden symptoms such as depressed mood; anxious, restless, or irritable behavior; panic attacks; or any unusual change in mood or behavior occur. Contact the doctor right away if any signs of suicidal thoughts or actions occur. THIS MEDICINE MAY CAUSE SERIOUS EYE PROBLEMS that could lead to permanent loss of vision if not treated. Seek medical attention right away if you experience new eye symptoms (eg, blurred vision or other vision changes, eye pain or redness). BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. FOR WOMEN, TAKING THIS MEDICINE while you are using birth control pills may decrease the effectiveness of your birth control pills. To prevent pregnancy, use an additional form of birth control while you are taking this medicine. IF YOU PLAN ON BECOMING PREGNANT, discuss with your doctor the benefits and risks of using this medicine during pregnancy. THIS MEDICINE IS EXCRETED in breast milk. IF YOU ARE OR WILL BE BREAST-FEEDING while you are using this medicine, check with your doctor or pharmacist to discuss the risks to your baby.
SIDE EFFECTS that may occur while taking this medicine include diarrhea, drowsiness, constipation, loss of appetite, nausea, numbness and tingling, decreased sweating, tiredness, or trouble sleeping. If they continue or are bothersome, check with your doctor. CONTACT YOUR DOCTOR IMMEDIATELY if you experience chest pain; loss of concentration; severe abdominal pain; significant weight loss; loss of coordination; memory problems; vision changes; unusual eye movement; fast, deep breathing; unusual bruising or bleeding; unusual tiredness; irregular heartbeat; tremor; change in speech; new or worsening mental or mood changes; or suicidal thoughts or actions. SEEK IMMEDIATE MEDICAL ATTENTION if you experience increased body temperature, unexplained fever, or very serious eye problems such as a sudden vision change or blurred vision, eye pain, or redness. AN ALLERGIC REACTION to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash, itching, swelling, dizziness, or trouble breathing. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your healthcare provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Drug interactions can result in unwanted side effects or prevent a medicine from doing its job. Use our drug interaction checker to find out if your medicines interact with each other. Check drug interactions
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include agitation; depression; lethargy; loss of coordination; mental impairment; seizures; severe drowsiness or dizziness; severe or persistent stomach pain; stupor; and vision problems (eg, blurred or double vision).
DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children and pets. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out.
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