I copied and pasted my last reveiw below, please read that now, before you read what I'm going to write now (see the *** below and read first). After reading that, please read this: I'm making a beg deal out of this because if you're like me, you suffered many years despite trying so many different remedies with no relief. As mentioned in my first review (below), I had a bad experience when taking 2 Dulcolax for the first time at night. However, I thought perhaps I should try taking one Dulcolax at night and continue taking Miralax (stool softner) in the morning (I put the Miralax, which is a powder, in my coffee, it's tasteless). I did not experience cramps or pain like the did the night I took 2 Dulcolax before bed, but it did take a few days for my body to get straightened out. Between the stool softner and the Dulcolax, which helps release the stool, I'm happy to report that I am the most "regular" than I have been in a decade. I knew I may have to adjust the amount of each the Miralex and Dulcolax, as well as the time of day I took each of them (if my stool was too loose, I'd take less Miralax, if I still experienced pain and gas, maybe I'd take the Dulcolax only 1ce a day instead of twice, etc). I beleive both products are required in order to benefit, don't try just one or the other. I admit it required a little patience on my part (in fact, I'm still adjusting), but I was desperate enough to do whatever it took, and if this didnt work, I'd try something else. Good luck! ***Like most, I too suffered severe cramping, gas, and yes pain pain pain! My doctor suggested that I take Miralax (stool softner) in the morning and Dulcolax at night. Last night I took 2 Dulcolax and at 3AM, and it wasnt pretty. However, I dont want to give up, and I'm thinking that perhaps my body just needs to get accustomed to this unfamiliar medication so I decided to continue using it, but will only take 1 tablet tonight. Maybe the gas, cramps and pain will subside after a few days of using it? My doctor told me that Exlax is a very nasty product (I used previously). It causes the muscles in the colon to stretch and stop functioning. He said that if you stop taking Exlax, the muscles will begin to function again, but that a stool softner is necessary in the interim. I'm hoping Dulcolax interacts differently with the muscles. I will try to comment in a few days or a week if anyone is interested in my results.