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Clinically Proven
Sam-e (S-adenosylmethionine) - Dietary Supplement
36 ~ Enteric Coated Tablets, 400mg

Mood Support - Joint Pain Relief - Liver Health
Improves Mood Naturally*

Limited Warranty to Consumers - Good Housekeeping Promises Replacement Or Refund If Defective

SAM-e (S-adenosylmethionine) is a naturally occurring compound found in all living organisms.  In humans, SAM-e is distributed throughout the body and is involved in many important biochemical processes.  Since significant amounts of SAM-e are not available through diet alone, the body is primarily responsible for producing its own SAM-e.  Scientists know that SAM-e declines as people age and that certain groups of people, including those with low mood and liver conditions, tend to have lower levels of SAM-e in their bodies.  Over 100 clinical studies involving thousands of people have proven that SAM-e supplementation benefits a multitude of body functions including:

• Mood Support - Enhances mood by promoting a healthy balance of neurotransmitters, dopamine and serotonin, which are part of overall healthy brain cell functions.*
• Joint Comfort - Relieves joint pain by helping to maintain joint cartilage which naturally deteriorates with physical activity and age.*
• Liver Health - Helps support detoxification and overall healthy liver functions.*

MoodPlus™ Sam-e is the same form of SAM-e available and administered for over 20 years by doctors in Europe.  It is the only form of SAM-e studied in over two decades of research, as well as the most documented form in respected medical journals.  Short and long-term studies have proven that SAM-e is a safe, non-toxic and efficacious product to support your health.*

Nature Made products containing SAM-e all use the naturally fermented SAM-e used and researched by doctors in Europe and the US in hundreds of clinical studies.  Some of those studies were recently subjected to a meta-analysis by the National Institute of Health's Agency for Healthcare Quality & Research meta-analysis "S-Adenosyl-L-Methionine for Treatment of Depression, Osteoarthritis, and Liver Disease"; 2002.  This review reached positive conclusions about the health benefits of SAM-e.*

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure or prevent any disease.

See package insert for more information.  You may also find a significant amount of detailed scientific information on SAM-e on the Internet, in popular books and in respected medical journals.

SAM-e tablets made to Nature Made's guaranteed purity and potency standards.
1-800-276-2878

Wellness Rewards Code (on package) visit ourwebsite & earn free vitamins.  Naturemade.com - Valid only for U.S. and Puerto Rico residents.

Made in Italy

Suggested Use:  Take 1 tablet per day.  The best time to take SAM-e is on an empty stomach at least 30 minutes before a meal.  See package insert for more details.