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Can blood pressure medicines cause impotence?

Can blood pressure medicines cause impotence?


answer for 'Can blood pressure medicines cause impotence?'Impotence, or erectile dysfunction (ED), can result from many medical conditions including high blood pressure, diabetes, and heart disease. Several different types of medications, including those for high blood pressure, can also cause it. As with most side effects, ED is more common with higher doses of medication. Changing to a different drug may solve the problem.

Some diuretics and beta-blockers are more likely to cause ED. As many as 25 to 50 percent of men who take the diuretics chlorothiazide (brand name Diuril), hydrochlorothiazide (Hydrodiuril), and spironolactone (Aldactone), or the beta blocker propranolol (Inderal), are affected. Other beta-blockers, such as atenolol (Tenormin) and metoprolol (Lopressor) cause this side effect in only 1 to 2 percent of men who take them.

Other types of blood pressure drugs rarely cause ED. Less than 1 percent of men who take the following drugs report the problem:

  • Angiotensin converting enzyme (ACE) inhibitors such as benazepril (Lotensin), enalapril (Vasotec), and lisinopril (Prinivil, Zestril)
  • Calcium channel blockers such as amlodipine (Norvasc), diltiazem (Cardizem), and nifedipine (Procardia)
  • Loop diuretics such as furosemide (Lasix)
  • Alpha blockers such as prazosin (Minipress) and doxazosin (Cardura)
  • Talk to your doctor if you experience impotence while on a blood pressure medication. Adjusting your dose or switching to a different medicine may make a tremendous difference.

    Sources:
    Kochar, M.S. “What is Causing Your patient's Sexual Dysfunction? Uncovering a Connection with Hypertension and Antihypertensive Therapy,” Postgraduate Medicine 106 (1999).
    Crenshaw, T.L., J.P. Goldberg. Sexual Pharmacology: Drugs That Affect Sexual Function. Crenshaw Writing Company, 1996.
    Applied Therapeutics: The Clinical Use of Drugs. Applied Therapeutics, 1995.
    Micromedex® Healthcare Series. Thomson Micromedex, 2007.
    Drug Facts and Comparisons. Facts & Comparisons, 2007.

    This answer prepared 5/23/2000.
    This information updated 1/2/2007.


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