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Does Cipro have any drug interactions?

Does Cipro have any drug interactions?


answer for 'Does Cipro have any drug interactions?'Cipro (generic name ciprofloxacin) is a prescription antibiotic medication used to treat infections caused by various bacteria. It is effective in treating a wide range of infections including urinary tract infections (UTIs), pneumonia, sinus, skin, and bone infections.

Cipro may interact with many other medicines to make them less effective or increase their side effects. Talk with your doctor or pharmacist about whether Cipro interacts with other medicines you are taking.

Examples of drugs that may interact with Cipro include theophylline (brand names: Theo-Dur, Uniphyl), warfarin (Coumadin), cyclosporine (Neoral, Sandimmune), didanosine (Videx), sucralfate (Carafate), iron supplements, caffeine and antacids (Tums, Maalox, Gaviscon).

Antacids or supplements that contain the minerals iron, zinc, calcium, magnesium, or aluminum bind to Cipro. This reduces the amount of the antibiotic that gets into your bloodstream and decreases Cipro’s ability to fight infection. You can continue to take an antacid product. But take your dose of Cipro at least two hours before or six hours after taking the antacid to avoid an interaction.

Tell your healthcare provider the names of all of the medicines you are taking, including over-the-counter and herbal medicines.

Drug interactions not included but in other sources:

  • tizanidine (Zanaflex);
  • chewable/buffered tablets or pediatric powder, other highly buffered drugs,
  • sulfonylurea glyburide
  • probenecid (Benemid)
  • methotrexate
  • nonsteroidal anti-inflammatory drug (NSAIDs) but not acetyl salicylic acid.
  • phenytoin (Dilantin)
  • Sources:
    Cipro Product Information, Bayer PharmaceuticalsHealthCare AG, 20006
    Drug Interaction Facts. Facts & Comparisons 4.0, 2006
    Micromedex® Healthcare Series, Thomson Micromedex Inc., 2006
    The Top 100 Drug Interactions: A Guide to Patient Management H&H Publications, 2001

    This answer prepared 10/15/2001.
    This information updated 1/23/2007.


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