Simvastatin is an HMG-CoA reductase inhibitor or "statin" used in combination with a low-cholesterol and low-fat diet to lower cholesterol (LDL) and triglyceride levels and to raise good cholesterol (HDL) levels in your blood. Simvastatin may also be used in certain adolescent patients, age 10 to 17 years, who have a genetically caused cholesterol problem. Simvastatin is not a cure for high cholesterol, but may help to control it. Simvastatin may also be used in certain patients to reduce the risk of blood vessel blockage, heart attack, stroke, and death due to heart disease. Simvastatin may also be used to treat other conditions as determined by your doctor.
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High cholesterol—also called hypercholesterolemia—is a condition in which the level of cholesterol in the blood is higher than normal, increasing your risk of heart disease and stroke..
HMG-CoA reductase inhibitors are a group of prescription drugs used to lower cholesterol, a white waxy substance that can stick to the inside of blood vessels, resulting in clogged arteries, heart disease, and strokes..