Learn more about usage, cautions, and possible side effects .
Chemical Name: MITOTANE (MYE-toe-tane)
This medicine is an adrenal cytotoxic agent used for treating adrenal cortical cancer that cannot be treated with surgery.
WARNING:This medicine may reduce the amount of natural steroid in the body. This may decrease your ability to recover from physical stress such as illness, injury, or surgery. Tell your doctor or dentist that you take this medicine before you receive any medical or dental care, emergency care, or surgery. Tell your doctor right away if you become ill or have an injury while you use this medicine. You may need to stop this medicine for a period of time. You may need to take a corticosteroid (eg, prednisone) until your body can make enough on its own. Check with your doctor for more information. Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking anticoagulants (eg, warfarin). DO NOT START OR STOP any medicine without doctor or pharmacist approval. Inform your doctor of any other medical conditions, including liver problems, allergies, pregnancy, or breast-feeding. USE OF THIS MEDICINE IS NOT RECOMMENDED if you have suffered severe trauma or shock. This medicine should not be used in CHILDREN; safety and effectiveness in children have not been confirmed. Contact your doctor or pharmacist if you have any questions or concerns about taking this medicine.
Follow the directions for taking this medicine provided by your doctor. TAKE THIS MEDICINE by mouth with or without food. This medicine may be started in a hospital setting until an individualized dose is determined. SWALLOW THIS MEDICINE WHOLE. Do not break, crush, or chew before swallowing. IF NAUSEA, VOMITING, OR LOSS OF APPETITE OCCURS, ask your doctor or pharmacist for ways to lessen these effects. TO MINIMIZE THE RISK OF SKIN EXPOSURE always wear gloves when handling bottles containing this medicine. BE SURE YOU KNOW how to properly handle and dispose of this medicine. Ask your doctor or pharmacist if you are unsure. STORE THIS MEDICINE at 77 degrees F (25 degrees C), away from heat, moisture, and light. Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Do not store in the bathroom. IF YOU MISS A DOSE of this medicine, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
DO NOT USE THIS MEDICINE IF you are allergic to any ingredient in this medicine. DO NOT EXCEED THE RECOMMENDED DOSE without checking with your doctor. LAB TESTS, such as adrenal function tests and neurological and behavioral tests, may be performed while you use this medicine. These tests may be used to monitor your condition or check for side effects.KEEP ALL DOCTOR AND LAB APPOINTMENTS. THIS MEDICINE MAY CAUSE DROWSINESS OR DIZZINESS. These effects may be worse if you take it with alcohol or certain medicines. Use this medicine with caution. DO NOT DRIVE OR PERFORM OTHER POSSIBLY UNSAFE TASKS until you know how you react to it. TELL YOUR DOCTOR OR DENTIST that you take this medicine before you receive any medical or dental care, emergency care, or surgery. BEFORE YOU BEGIN TAKING ANY NEW MEDICINES, either prescription or over-the-counter, check with your doctor or pharmacist. FOR WOMEN: IF YOU BECOME PREGNANT, contact your doctor. You will need to discuss the benefits and risks of using this medicine while you are pregnant. IT IS NOT KNOWN IF THIS MEDICINE IS FOUND in breast milk. DO NOT BREAST-FEED while taking this medicine.
SIDE EFFECTS that may occur while taking this medicine include diarrhea; dizziness; drowsiness; lack of energy; loss of appetite; nausea; tiredness; or vomiting. If they continue or are bothersome, check with your doctor. CONTACT YOUR DOCTOR IMMEDIATELY if you experience blood in the urine; blurred vision, double vision, or other vision changes; fainting; fever; or severe or persistent dizziness, drowsiness, headache, lightheadedness, or tiredness. AN ALLERGIC REACTION to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Drug interactions can result in unwanted side effects or prevent a medicine from doing its job. Use our drug interaction checker to find out if your medicines interact with each other. Check drug interactions
If overdose is suspected, contact your local poison control center or emergency room immediately.
DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children and pets. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out.
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