Learn more about usage, cautions, and possible side effects .
Chemical Name: KETOCONAZOLE (kee-toe-KON-a-zole)
This medicine is an imidazole antifungal agent used to treat certain fungal infections.
WARNING: This medicine has been shown to cause serious and sometimes fatal liver problems. Contact your doctor immediately if you experience symptoms of liver toxicity such as unusual fatigue, yellowing of the eyes or skin, dark urine, pale stools, loss of appetite, abdominal pain, vomiting, or severe or persistent nausea. Your doctor will perform liver function tests before you begin taking this medicine and periodically during treatment. Use of this medicine along with certain other medicines may increase your risk of serious and sometimes fatal heart problems, including irregular heartbeat. DO NOT TAKE THIS MEDICINE IF YOU ARE ALSO TAKING astemizole, cisapride, or terfenadine. Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. DO NOT TAKE THIS MEDICINE if you are also taking an aldosterone blocker (such as eplerenone), conivaptan, dofetilide, an ergot alkaloid (such as ergotamine), erythromycin, midazolam, nevirapine, pimozide, a quinazoline (such as alfuzosin), quinidine, rifabutin, rifampin, triazolam, or a 5-HT receptor agonist (eg, eletriptan). ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you take other prescription and nonprescription medicines (eg, used for infections, HIV, seizures, anxiety, sleep, heartburn, diabetes, high cholesterol, heart problems, high blood pressure, allergies, irregular heartbeat, pain, blood thinning, asthma, migraines, mood or mental problems, cancer, prostate problems, immune system suppression, erectile dysfunction, urinary problems, or contraception [birth control]), multivitamin products, and herbal or dietary supplements. Inform your doctor of any other medical conditions, including low stomach acid (such hypochlorhydria), allergies, pregnancy, or breast-feeding. Tell your doctor if you have a history of regular alcohol use, abuse, or dependence; liver problems; or blood problems (such as porphyria). USE OF THIS MEDICINE IS NOT RECOMMENDED IF you have a fungal infection in the brain membranes (fungal meningitis). Contact your doctor or pharmacist if you have any questions or concerns about taking this medicine.
Follow the directions for using this medicine provided by your doctor. This medicine may be taken on an empty stomach or with food. DO NOT TAKE ANTACIDS within 1 hour before or 2 hours after you take this medicine. If you also take an anticholinergic (such as hyoscyamine), H2 antatgonist (such as famotidine), or a proton pump inhibitor (such as omeprazole), take this medicine at least 2 hours before you take your anticholinergic, H2 antagonist, or proton pump inhibitor. STORE THIS MEDICINE at room temperature in a tightly-closed container, away from heat and light. Take this medicine regularly to receive the most benefit from it. Taking it at the same time each day will help you to remember. TO CLEAR UP YOUR INFECTION COMPLETELY, continue taking this medicine for the full course of treatment even if you feel well. Do not miss any doses. IF YOU MISS A DOSE OF THIS MEDICINE, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
DO NOT TAKE THIS MEDICINE if you have had an allergic reaction to it or are allergic to any ingredient in this product. IF YOU EXPERIENCE difficulty breathing; tightness of chest; swelling of eyelids, face, or lips; or if you develop a rash or hives, tell your doctor immediately. Do not take any more of this medicine unless your doctor tells you to do so. DO NOT EXCEED THE RECOMMENDED DOSE without checking with your doctor. Laboratory and/or medical tests, including liver function may be performed to monitor your progress or to check for side effects. KEEP ALL DOCTOR AND LABORATORY APPOINTMENTS while you are taking this medicine. BEFORE YOU HAVE ANY MEDICAL OR DENTAL TREATMENTS, EMERGENCY CARE, OR SURGERY, tell the doctor or dentist that you are using this medicine. USE OF ALCOHOL WITH THIS MEDICINE has rarely caused symptoms such as flushing, rash, swelling of the hands and feet, nausea, and headache. Talk with your doctor before you drink alcohol while you are using this medicine. THIS MEDICINE MAY CAUSE dizziness or drowsiness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to this medicine. Using this medicine alone, with other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. CAUTION IS ADVISED WHEN USING THIS MEDICINE IN CHILDREN because they may be more sensitive to the effects of the medicine. FOR WOMEN TAKING BIRTH CONTROL PILLS: this medicine may decrease the effectiveness of your birth control pills. To prevent pregnancy, use an additional form of birth control while you are taking this medicine. IF YOU PLAN ON BECOMING PREGNANT, discuss with your doctor the benefits and risks of using this medicine during pregnancy. THIS MEDICINE IS EXCRETED IN BREAST MILK. DO NOT BREAST-FEED while taking this medicine. IF YOU HAVE DIABETES, this medicine may affect your blood sugar. Check blood sugar levels closely and ask your doctor before adjusting the dose of your diabetes medicine.
SIDE EFFECTS that may may occur while using this medicine include dizziness, drowsiness, nausea, stomach pain, or stomach upset. If they continue or are bothersome, check with your doctor. CHECK WITH YOUR DOCTOR AS SOON AS POSSIBLE if you experience bloating; decreased sexual ability; fever, chills, or persistent sore throat; loss of appetite; or numbness or tingling of the hands or feet. CONTACT YOUR DOCTOR IMMEDIATELY if you experience dark urine, depression or thoughts of suicide, irregular heartbeat, pale stools, severe or persistent nausea, vomiting, or stomach pain, swollen or tender abdomen, unusual bruising or bleeding, unusual tiredness or fatigue, vision changes, or yellowing of the skin or eyes. An allergic reaction to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash, itching, swelling, severe dizziness, or trouble breathing. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your healthcare provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Drug interactions can result in unwanted side effects or prevent a medicine from doing its job. Use our drug interaction checker to find out if your medicines interact with each other. Check drug interactions
If overdose is suspected, contact your local poison control center or emergency room immediately.
DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children and pets. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out.
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