Learn more about usage, cautions, and possible side effects .
Chemical Name: PIOGLITAZONE (pye-oh-GLI-ta-zone)
This medicine is used to treat type 2 diabetes by reducing the resistance your body has to insulin. It is used either alone or in combination with other anti-diabetes medicines, including metformin or insulin, as part of a diet and exercise program.
WARNING: THIAZOLIDINEDIONE ANTIDIABETICS SUCH AS THIS MEDICINE MAY CAUSE OR WORSEN HEART FAILURE IN SOME PATIENTS. Tell your doctor if you have a history of heart failure. This medicine should not be used to treat patients with moderate to severe heart failure. You will be monitored for signs of heart failure when you start this medicine and when your dose increases. CONTACT YOUR DOCTOR AT ONCE if you develop swelling of the hands, ankles, or feet; shortness of breath; or sudden, unexplained weight gain. Your doctor may need to stop your medicine or change your dose. Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking gemfibrozil, insulin, oral antidiabetic medicines (such as glipizide), rifampin, or anticoagulants (such as warfarin). USE OF THIS MEDICINE IS NOT RECOMMENDED if you have newly diagnosed or worsening heart failure (acute congestive heart failure), type 1 diabetes, diabetic ketoacidosis, active liver disease, or experienced jaundice with troglitazone. Tell your doctor if you have a history of liver problems, abnormal liver function tests, heart problems (eg, congestive heart failure), or eye or vision problems. Inform your doctor of any other medical conditions including diabetic ketoacidosis (a severe problem associated with diabetes), swelling problems (edema), allergies, pregnancy, or breast-feeding. USE OF THIS MEDICINE in children under age 18 is not recommended. Discuss with your doctor the risks and benefits of giving this medicine to your child. Contact your doctor or pharmacist if you have any questions or concerns about taking this medicine.
Follow the directions for using this medicine provided by your doctor. An additional patient information leaflet is available with this medicine. Ask your doctor, nurse, or pharmacist any questions that you may have about this information. This medicine may be taken on an empty stomach or with food. STORE THIS MEDICINE at room temperature at 77 degrees F (25 degrees C) in a tightly-closed container, away from heat, moisture, and light. Brief storage between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Taking this medicine at the same times each day will help you to remember. CONTINUE TO TAKE THIS MEDICINE even if you feel well. Do not miss any doses. IF YOU MISS A DOSE OF THIS MEDICINE, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do NOT take 2 doses at once.
DO NOT STOP USING THIS MEDICINE or other diabetes medicine without first checking with your doctor. CHECK WITH YOUR DOCTOR before adjusting the dose of your diabetes medicine or changing your diet. IF YOU ARE TAKING THIS MEDICINE WITH OTHER DIABETES MEDICINE, you are at an increased risk of becoming hypoglycemic (low blood sugar). Signs of hypoglycemia include an increased heartbeat, headache, sweating, tremor, increased hunger, changes in vision, nervousness, or tiredness. Discuss with your doctor or nurse how to handle hypoglycemic reactions. THIS MEDICINE MAY BE ASSOCIATED WITH AN INCREASED RISK OF BONE FRACTURE IN SOME WOMEN. Inform your doctor if you have a history of bone fracture, low calcium intake, osteoporosis, or weakened bones. This medicine may be associated with an increased risk of bladder cancer. Discuss any questions or concerns with your doctor. KEEP ALL DOCTOR AND LABORATORY APPOINTMENTS while you are using this medicine. Laboratory and/or medical tests such as fasting blood sugar, hemoglobin A1C, eye examinations, and liver function may be done to monitor your progress or to check for side effects. BEFORE YOU HAVE ANY MEDICAL OR DENTAL TREATMENTS, EMERGENCY CARE, OR SURGERY, tell the doctor or dentist that you are using this medicine. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. FOR WOMEN TAKING BIRTH CONTROL PILLS: this medicine may decrease the effectiveness of your birth control pill. To prevent pregnancy, use an additional form of birth control. FOR WOMEN: this medicine may increase your chance of pregnancy by causing ovulation to resume in premenopausal women who have not been ovulating. IF YOU PLAN ON BECOMING PREGNANT, discuss with your doctor the benefits and risks of using this medicine during pregnancy. IT IS UNKNOWN IF THIS MEDICINE IS EXCRETED in breast milk. DO NOT BREAST-FEED while taking this medicine.
A SIDE EFFECT that may occur while taking this medicine is sore throat. If it continues or is bothersome, check with your doctor. CONTACT YOUR DOCTOR IMMEDIATELY if you experience the following side effects: bloating or swelling of ankles, feet, or hands; blurred vision or other vision changes; chest pain; rapid weight gain; shortness of breath; fatigue; unexplained nausea or vomiting; stomach pain; loss of appetite; unusual thirst; unusual amount of urine; dark urine; or yellowing of the skin or eyes. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your healthcare provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Drug interactions can result in unwanted side effects or prevent a medicine from doing its job. Use our drug interaction checker to find out if your medicines interact with each other. Check drug interactions
If overdose is suspected, contact your local poison control center or emergency room immediately.
FOLLOW THE DIETARY AND EXERCISE PLAN provided by your doctor. Carry an identification card at all times that says you are diabetic. Monitor your blood sugar levels regularly according to your doctor's directions. If your blood sugar level is often higher or lower than it should be and you are taking this medicine according to directions, check with your doctor. IT MAY BE HARDER TO CONTROL YOUR BLOOD SUGAR DURING TIMES OF STRESS such as fever, infection, injury, or surgery. Talk to your doctor about how to control your blood sugar if any of these occur. DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS PRODUCT out of the reach of children. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out.
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